Meehan, James.
Cancer Biomarker Research and Personalized
Medicine : учебное пособие / ed. James Meehan. - Edinburgh : MDPI,
2022. - 415 p. : il. - (Journal of Personalized Medicine). -
ISBN 978-3-0365-3918-8 : Б. ц.
Рубрики: Медицина
Кл.слова (ненормированные):
PERSONALIZED,
MEDICINE
Аннотация: Biomarkers are measures of a biological state.
The treatment of individual patients based on particular factors,
such as biomarkers, distinguishes standard, generalized treatment
plans from personalized medicine. Even though personalized medicine
is applicable to most branches of medicine, the field of oncology
is perhaps where it is most easily employed. Cancer is a
heterogeneous disease; although patients may be diagnosed
histologically with the same cancer type, their tumors can comprise
varying tumor microenvironments and molecular characteristics that
can impact treatment response and prognosis. There has been a major
drive over the past decade to try and realize personalized cancer
medicine through the discovery and use of disease-specific
biomarkers. This book, entitled "Cancer Biomarker Research and
Personalized Medicine", encompasses 22 publications from colleagues
working on a diverse range of cancers, including prostate, breast,
ovarian, head and neck, liver, gastric, bladder, colorectal, and
kidney. The biomarkers assessed in these studies include genes,
intracellular or secreted proteins, exosomes, DNA, RNA, miRNA,
circulating tumor cells, circulating immune cells, in addition to
radiomic features.
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